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Physical Activity Linked with Improved Cancer Survival, New ACS Study Finds

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A new large analysis led by American Cancer Society (ACS) researchers shows engaging in leisure-time moderate-to-vigorous physical activity (MVPA) after a cancer diagnosis improves survival for people with several cancer types, including bladder, breast, colon, endometrial, kidney, lung, oral, prostate, rectal, and respiratory cancer. Image for illustration purposes
A new large analysis led by American Cancer Society (ACS) researchers shows engaging in leisure-time moderate-to-vigorous physical activity (MVPA) after a cancer diagnosis improves survival for people with several cancer types, including bladder, breast, colon, endometrial, kidney, lung, oral, prostate, rectal, and respiratory cancer. Image for illustration purposes
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By American Cancer Society (ACS) 

Newswise — A new large analysis led by American Cancer Society (ACS) researchers shows engaging in leisure-time moderate-to-vigorous physical activity (MVPA) after a cancer diagnosis improves survival for people with several cancer types, including bladder, breast, colon, endometrial, kidney, lung, oral, prostate, rectal, and respiratory cancer. This is the first longitudinal study of the relationships between postdiagnosis physical activity and overall mortality in bladder and oral cavity cancer survivors and is the largest study to quantify associations within survivors of endometrial, kidney, and lung cancer. The findings are published today in the Journal of the National Cancer Institute (JNCI).

“For decades, it’s been known that consistent exercise can help people live healthier lives,” said Dr. Erika Rees-Punia, senior principal scientist, population science research at the American Cancer Society and lead author of the study. “Our findings bring more critical evidence that being physically active after a cancer diagnosis can bring a meaningful impact on your likelihood of survival.”

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Researchers pooled data from six U.S.-based studies, including 90,844 cancer survivors, with an average age of 67 years, among whom 45,477 died during an average of 10.9 years of follow-up. Specific hazard ratios and 95% confidence intervals for associations of MVPA assessed one year or more after a cancer diagnosis and all-cause mortality were calculated using proportional hazards models and then pooled using random effects meta-analysis. Models were adjusted for age, sex, race/ethnicity, smoking status, alcohol use, cancer treatment, and stage.

Study results showed that compared to no MVPA, engaging in recommended amounts of MVPA after a cancer diagnosis was related to better overall survival in participants with a history of one of ten cancer types: oral, endometrial, lung, rectal, respiratory, bladder, kidney, prostate, colon, and breast. The recommended amount of MVPA is 7.5 to under 15 Metabolic Equivalent of Task or MET hours per week, equivalent to 2.5 – 5 hours of brisk walking per week.

“The effects of cancer treatment can wear you down physically and mentally,” Rees-Punia added. “This can make exercise feel like a daunting task, but doing some exercise is better than doing none. Finding an exercise that you enjoy or exercising with a friend can make it more approachable.”

Other ACS researchers contributing to the study include Dr. Lauren TerasChristina NewtonDr. Lauren Bates-FraserDen E Bloodworth, and senior author Dr. Alpa Patel.

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