loader image
Tuesday, October 7, 2025
80.9 F
McAllen
- Advertisement -

Cell-based influenza vaccine provides protection against the flu in children

Translate to Spanish or other 102 languages!

A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study. CDC Image

Mega Doctor News

- Advertisement -

By Murdoch Childrens Research Institute

Newswise — A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study.

The research found the cell-based quadrivalent influenza vaccine (QIVc) produced a sufficient immune response in children aged two to 18 years. The lead investigator on the study was Professor Terry Nolan, head of the Vaccine and Immunization Research Group (VIRGo) at the Murdoch Children’s Research Institute (MCRI), and the Peter Doherty Institute for Infection and Immunity at the University of Melbourne.

- Advertisement -

The findings, published in The New England Journal of Medicine, were the first on the absolute efficacy of a cell-based influenza vaccine in children as young as two years of age.

The randomized controlled study involved 4514 participants across Australia, Thailand, Estonia, Finland, Lithuania, Poland, Spain, and the Philippines. The overall vaccine efficacy was 54.6 per cent, meeting the pre-specified endpoint for success and showing benefit across three influenza seasons and all eight countries.

QIVc uses a cell-based flu vaccine production process, an alternative to traditional egg-based manufacturing where reference influenza viruses are grown in the yolk of fertilized hens eggs. But this can result in mutation of the influenza virus leading to an antigenic mismatch between the circulating reference and inactivated strains contained within the seasonal flu vaccine. 

Professor Nolan said because cell-based flu vaccines, grown in animal cells, were designed to produce an exact match to the World Health Organization’s selected influenza strains by avoiding egg-adapted changes, they could potentially provide greater effectiveness. 

- Advertisement -

Professor Nolan said cell-based vaccine technology may also offer additional advantages including increased scalability and production speed in the event of an influenza pandemic.

In a typical year, 5–15 per cent of the world’s population contracts influenza and there are up to 650,000 respiratory-related deaths. Deaths most commonly occur in high-risk groups, including young children, the elderly, and people with chronic health conditions.

- Advertisement -
- Advertisement -

- Advertisement -

More Articles

Unidos Contra la Diabetes to Host 2026 Mini-Symposium and Annual Dia-Beat-IT Health Fair, Nov. 5th

Unidos Contra la Diabetes (UCD) has announced that its 2026 Mini-Symposium and Annual Dia-Beat-IT Health Fair is less than a month away. Moises Arjona Jr., MS, CHWI, Collective Impact Director for UCD, reminded community partners and stakeholders of the upcoming event, encouraging participation and support.

STHS Hosting Muscle Strengthening Session for Seniors for Fall Prevention, Oct. 8th

Mega Doctor News Muscle loss, a condition referred to as sarcopenia, is a...

More Women Under 50 Are Getting Breast Cancer

Mega Doctor News By American College of Surgeons (ACS) Newswise — CHICAGO — About 1...

DHR Health Breast Cancer Symposium, Oct. 11th 

To support providers in the community, the DHR Health Continuing Medical Education Department will host the Breast Cancer Symposium on Saturday, October 11, at the Edinburg Conference Center at Renaissance, located at 118 Paseo del Prado.
- Advertisement -
×