How Colorectal Cancer Differs in Younger Adults

March is Colorectal Cancer Awareness Month. New research from Cleveland Clinic shows how the tumor microbiome in younger adults appears to be different.

Translate to Spanish or other 102 languages!

He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms.  Image for illustration purposes
He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms.  Image for illustration purposes
- Advertisement -

CLEVELAND CLINIC – March is Colorectal Cancer Awareness Month, and reports show the number of cases among younger adults is rising. 

It’s unclear exactly why that is, but research from Cleveland Clinic could help shed some light. 

“What we analyzed in our recent research was looking at the cancers that came from younger people and cancers that occurred in older people, and we found that the microbiome of younger onset colorectal cancer is actually different than the microbiome of older onset colorectal cancer,” said Alok Khorana, MD, oncologist for Cleveland Clinic who led the research.

- Advertisement -

Dr. Khorana said the microbiome of a tumor is made up of human and non-human cells, and in this study, they found there was more bacteria in the tumor microbiome of younger adults with colorectal cancer. 

So, why is that? 

He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms. 

“So, this really leads us to search for more clues as to why this is happening. Is it related to diet? Is it related to environment? Is it related to antibiotic use in younger people? Is it related to exposures of babies, children, or adolescents? We don’t fully understand that. This is another step in trying to figure out what is happening,” said Dr. Khorana.

- Advertisement -

Dr. Khorana said the hope from this research is that it can ultimately aid in colorectal cancer prevention and treatment options in the future. 

- Advertisement -
- Advertisement -

- Advertisement -

More Articles

Texas Adds New Condition to Mandatory Newborn Screening Tests

The Texas Department of State Health Services added a new enzyme deficiency test on June 1, 2026, to its newborn screening panel, meaning that all Texas newborns are now tested for 60 rare, genetic conditions. Tests for hearing loss and critical congenital heart disease are additional point-of-service tests typically conducted by the birthing center. 

Pancreatic Cancer Patients Gain Early Access to Experimental Drug Daraxonrasib Following Fast-Track FDA Decision

The U.S. Food and Drug Administration is announcing that it issued a “safe to proceed” letter to Revolution Medicines, allowing the sponsor to initiate an expanded access treatment protocol (EAP) for its experimental pancreatic cancer drug, daraxonrasib.

STHS GME Consortium Encourages Community to “Walk with a Doc”, June 6th

Mega Doctor News In an era defined by high-intensity workouts, wearable fitness trackers and advanced training techniques, one of simplest...

Study: Menopause Hormone Therapy Declines Nationwide Despite Proven Benefits

Hormone therapy use among women in the U.S. remains low, even though it's an effective treatment for many menopause symptoms, according to a new Mayo Clinic study published in Mayo Clinic Proceedings.
- Advertisement -