How Colorectal Cancer Differs in Younger Adults

March is Colorectal Cancer Awareness Month. New research from Cleveland Clinic shows how the tumor microbiome in younger adults appears to be different.

Translate to Spanish or other 102 languages!

He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms.  Image for illustration purposes
He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms.  Image for illustration purposes
- Advertisement -

CLEVELAND CLINIC – March is Colorectal Cancer Awareness Month, and reports show the number of cases among younger adults is rising. 

It’s unclear exactly why that is, but research from Cleveland Clinic could help shed some light. 

“What we analyzed in our recent research was looking at the cancers that came from younger people and cancers that occurred in older people, and we found that the microbiome of younger onset colorectal cancer is actually different than the microbiome of older onset colorectal cancer,” said Alok Khorana, MD, oncologist for Cleveland Clinic who led the research.

- Advertisement -

Dr. Khorana said the microbiome of a tumor is made up of human and non-human cells, and in this study, they found there was more bacteria in the tumor microbiome of younger adults with colorectal cancer. 

So, why is that? 

He said they are not entirely sure, but it could be possible that the way colorectal cancer develops in younger adults is driven by a different group of microorganisms. 

“So, this really leads us to search for more clues as to why this is happening. Is it related to diet? Is it related to environment? Is it related to antibiotic use in younger people? Is it related to exposures of babies, children, or adolescents? We don’t fully understand that. This is another step in trying to figure out what is happening,” said Dr. Khorana.

- Advertisement -

Dr. Khorana said the hope from this research is that it can ultimately aid in colorectal cancer prevention and treatment options in the future. 

- Advertisement -
- Advertisement -

- Advertisement -

More Articles

Study Reveals Link Between Parent and Child Weight Is Mostly Genetic

The link between parents’ body mass index (BMI) and their children’s BMI in childhood is driven largely by genetic inheritance, rather than by any direct biological effects of parental weight during pregnancy, a new study suggests.

The Genetic Armor Defeating Colorectal Cancer

A team of scientists from the Barbara Ann Karmanos Cancer Institute, Wayne State University, and institutions across the U.S., have published a landmark paper on the role of TGFBR1*6A, a naturally occurring genetic mutation in the TGFBR1 gene found in approximately 14 percent of the general population. Image for illustration purposes

Why CKM Syndrome Requires a Coordinated Care Point Person

When the term “cardiovascular-kidney-metabolic syndrome” was created in 2023 to define how heart disease, kidney disease, obesity and diabetes are connected, one goal was to help health professionals understand the benefits of working together.

How Long is Too Long to Fall Asleep?

How long does it take you to fall asleep? Sleep experts call this sleep latency, and they say there’s a typical range for how long it takes most people to drift off.
- Advertisement -