loader image
Monday, May 19, 2025
98.7 F
McAllen
We Welcome your Press Release
- Advertisement -

Oxygen-delivering hydrogel accelerates diabetic wound healing

Translate to Spanish or other 102 languages!

Jianjun Guan, professor of mechanical engineering and materials science at the McKelvey School of Engineering at Washington University in St. Louis, has developed a hydrogel that delivers oxygen to a wound. Image for illustration purposes.

Mega Doctor News

- Advertisement -

By Washington University in St. Louis

Newswise – About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can become chronic, leading to poor quality of life and potential amputation.

Jianjun Guan, professor of mechanical engineering and materials science at the McKelvey School of Engineering at Washington University in St. Louis, has developed a hydrogel that delivers oxygen to a wound, which decreases inflammation, helps remodel tissue and accelerates healing. Results of the work, which were in a mouse model, are published Aug. 28 in Science Advances. Ya Guan, a doctoral student, and Hong Niu, a postdoctoral research associate, both in Guan’s lab, are co-first authors.

- Advertisement -

Guan’s hydrogel delivers oxygen to the wound using microspheres that gradually release oxygen to interact with the cells through an enzyme on their surface that converts what is inside of the microsphere into oxygen. The oxygen is delivered to the wound over about a two-week period, and inflammation and swelling decrease, prompting healing.

“The oxygen has two roles: one, to improve skin cell survival under the low-oxygen condition of the diabetic wound; and two, oxygen can stimulate the skin cells to produce growth factors necessary for wound repair,” Guan said.

- Advertisement -
- Advertisement -

- Advertisement -

More Articles

IDEA Public Schools 25th Anniversary Gala, May 22nd

Mega Doctor News IDEA Public Schools will be hosting its annual Dinner and...

STHS Highlights Impact of Chronic Stress on Physical & Mental Health, May 25th

Mega Doctor News If you are struggling with the pressures of daily life, you are certainly not...

IDEA Public Schools Class of 2025 Celebrates College Signing Day

Mega Doctor News The McAllen Convention Center was alive with excitement as...

STHS McAllen Launches Parkinson’s Disease Support Group

Mega Doctor News An unpredictable and difficult neurological disorder, life with Parkinson’s disease...
- Advertisement -
×