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What if a simple injection could instruct your body to destroy diseases like cancer or HIV? This remarkable possibility could soon become reality thanks to pioneering research at Penn Medicine.

Dr. Carl June and Dr. Drew Weissman are collaborating to modify messenger RNA (mRNA) to program cells to produce powerful cancer-killing CAR T-cells directly inside the body. By combining mRNA technology with CAR T-cells, this breakthrough treatment could be administered via direct injection like a standard drug.

The simplified, affordable nature expands its potential to treat not just cancer but autoimmune diseases, HIV, and many other illnesses.

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